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Handcuffing reversal is facilitated by proteases and replication initiator monomers

Specific nucleoprotein complexes are formed strictly to prevent over-initiation of DNA replication. An example of those is the so-called handcuff complex, in which two plasmid molecules are coupled together with plasmid-encoded replication initiation protein (Rep). In this work, we elucidate the mec...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Bury, Katarzyna, Wegrzyn, Katarzyna, Konieczny, Igor
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397158/
https://ncbi.nlm.nih.gov/pubmed/28335002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx166
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