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Comparison of toxicity values across zebrafish early life stages and mammalian studies: Implications for chemical testing

With the high cost and slow pace of toxicity testing in mammals, the vertebrate zebrafish has become a tractable model organism for high throughput toxicity testing. We present here a meta-analysis of 600 chemicals tested for toxicity in zebrafish embryos and larvae. Nineteen aggregated and 57 indiv...

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Detalhes bibliográficos
Publicado no:Reprod Toxicol
Main Authors: Ducharme, Nicole A., Reif, David M., Gustafsson, Jan-Ake, Bondesson, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396953/
https://ncbi.nlm.nih.gov/pubmed/25261610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reprotox.2014.09.005
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