Soluble cytotoxic T-lymphocyte antigen 4: a favorable predictor in malignant tumors after therapy

PURPOSE: Soluble cytotoxic T-lymphocyte antigen 4 (sCTLA-4), one of the isoforms of CTLA-4, was discovered to be critical in downregulating the negative signal of CTLA-4 in T-cell responses. Contrary to the classical immunosuppressive effect of CTLA-4, its immunoregulatory function might be complica...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Liu, Qiqi, Hu, Pingping, Deng, Guodong, Zhang, Jingxin, Liang, Ning, Xie, Jian, Qiao, Lili, Luo, Hui, Zhang, Jiandong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396933/
https://ncbi.nlm.nih.gov/pubmed/28442923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S128451
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