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Asynchronous replication of homologous loci on human active and inactive X chromosomes.

The two X chromosomes in mammalian females replicate asynchronously, the inactive later than the active one. Using BrdUrd-sensitive restriction and UV irradiation to identify newly synthesized DNA directly on Southern blots, and restriction fragment length differences to discriminate alleles on acti...

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Bibliographic Details
Main Authors: Schmidt, M, Migeon, B R
Format: Artigo
Language:Inglês
Published: 1990
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC53967/
https://ncbi.nlm.nih.gov/pubmed/2339112
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