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Absence of non-histone protein complexes at natural chromosomal pause sites results in reduced replication pausing in aging yeast cells

There is substantial evidence that genomic instability increases during aging. Replication pausing (and stalling) at difficult-to-replicate chromosomal sites may induce genomic instability. Interestingly, in aging yeast cells we observed reduced replication pausing at various natural replication pau...

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Bibliografski detalji
Izdano u:Cell Rep
Glavni autori: Cabral, Marleny, Cheng, Xin, Singh, Sukhwinder, Ivessa, Andreas S.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396545/
https://ncbi.nlm.nih.gov/pubmed/27829146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.050
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