Epigenetic Reactivation of RASSF1A by Phenethyl Isothiocyanate (PEITC) and promotion of apoptosis in LNCaP cells

Epigenetic silencing of tumor suppressor genes is a phenomenon frequently observed in multiple cancers. Ras-association domain family 1 isoform A (RASSF1A) is a well-characterized tumor suppressor that belongs to the Ras-association domain family. Several studies have demonstrated that hypermethylat...

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Detalhes bibliográficos
Publicado no:Pharmacol Res
Main Authors: Boyanapalli, Sarandeep S.S., Li, Wenji, Fuentes, Francisco, Guo, Yue, Ramirez, Christina N., Gonzalez, Ximena-Parades, Pung, Douglas, Kong, Ah-Ng Tony
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396455/
https://ncbi.nlm.nih.gov/pubmed/27818231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2016.10.021
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