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Clinical-pharmacogenetic models for personalized cancer treatment: application to malignant mesothelioma

Large interindividual differences in treatment outcome are observed in cancer patients undergoing chemotherapy. Our aim was to develop and validate clinical-pharmacogenetic prediction models of gemcitabine/cisplatin or pemetrexed/cisplatin treatment outcome and develop an algorithm for genotype-base...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Goričar, Katja, Kovač, Viljem, Dolžan, Vita
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396189/
https://ncbi.nlm.nih.gov/pubmed/28422153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46537
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