Exome Analysis of Rare and Common Variants within the NOD Signaling Pathway

Pediatric inflammatory bowel disease (pIBD) is a chronic heterogeneous disorder. This study looks at the burden of common and rare coding mutations within 41 genes comprising the NOD signaling pathway in pIBD patients. 136 pIBD and 106 control samples underwent whole-exome sequencing. We compared th...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Andreoletti, Gaia, Shakhnovich, Valentina, Christenson, Kathy, Coelho, Tracy, Haggarty, Rachel, Afzal, Nadeem A, Batra, Akshay, Petersen, Britt-Sabina, Mort, Matthew, Beattie, R. Mark, Ennis, Sarah
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396125/
https://ncbi.nlm.nih.gov/pubmed/28422189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46454
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