Comprehensive molecular exploration identified promoter DNA methylation of the CRBP1 gene as a determinant of radiation sensitivity in rectal cancer

BACKGROUND: Neoadjuvant chemoradiotherapy (NCRT) for advanced rectal cancer (RC) is a well-evidenced therapy; however, some RC patients have no therapeutic response. Patient selection for NCRT so that non-responsive patients are excluded has been subjective. To date, no molecular markers indicating...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Yokoi, K, Yamashita, K, Ishii, S, Tanaka, T, Nishizawa, N, Tsutsui, A, Miura, H, Katoh, H, Yamanashi, T, Naito, M, Sato, T, Nakamura, T, Watanabe, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5396119/
https://ncbi.nlm.nih.gov/pubmed/28291773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.65
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