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The risk of bias in randomized controlled trials in otorhinolaryngology: hardly any improvement since 1950

BACKGROUND: Randomized Controlled Trials (RCTs) represent the most valuable study design to evaluate the effectiveness of therapeutic interventions. However, flaws in design, conduct, analysis, and reporting of RCTs can cause the effect of an intervention to be under- or overestimated. These biased...

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Veröffentlicht in:BMC Ear Nose Throat Disord
Hauptverfasser: Peters, Jeroen P. M., Stegeman, Inge, Grolman, Wilko, Hooft, Lotty
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395869/
https://ncbi.nlm.nih.gov/pubmed/28428729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12901-017-0036-x
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