Signaling Mediated by Toll-Like Receptor 5 Sensing of Pseudomonas aeruginosa Flagellin Influences IL-1β and IL-18 Production by Primary Fibroblasts Derived from the Human Cornea

Pseudomonas aeruginosa is the principal cause of bacterial keratitis worldwide and overstimulation of the innate immune system by this organism is believed to contribute significantly to sight loss. In the current study, we have used primary human corneal fibroblast (hCF) cells as an ex vivo model o...

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Vydáno v:Front Cell Infect Microbiol
Hlavní autoři: Cendra, Maria del Mar, Christodoulides, Myron, Hossain, Parwez
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395653/
https://ncbi.nlm.nih.gov/pubmed/28469996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00130
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