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Signaling Mediated by Toll-Like Receptor 5 Sensing of Pseudomonas aeruginosa Flagellin Influences IL-1β and IL-18 Production by Primary Fibroblasts Derived from the Human Cornea

Pseudomonas aeruginosa is the principal cause of bacterial keratitis worldwide and overstimulation of the innate immune system by this organism is believed to contribute significantly to sight loss. In the current study, we have used primary human corneal fibroblast (hCF) cells as an ex vivo model o...

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發表在:Front Cell Infect Microbiol
Main Authors: Cendra, Maria del Mar, Christodoulides, Myron, Hossain, Parwez
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395653/
https://ncbi.nlm.nih.gov/pubmed/28469996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00130
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