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SimBoost: a read-across approach for predicting drug–target binding affinities using gradient boosting machines

Computational prediction of the interaction between drugs and targets is a standing challenge in the field of drug discovery. A number of rather accurate predictions were reported for various binary drug–target benchmark datasets. However, a notable drawback of a binary representation of interaction...

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Detalhes bibliográficos
Publicado no:J Cheminform
Main Authors: He, Tong, Heidemeyer, Marten, Ban, Fuqiang, Cherkasov, Artem, Ester, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395521/
https://ncbi.nlm.nih.gov/pubmed/29086119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13321-017-0209-z
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