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NG-methyl-L-arginine inhibits tumor necrosis factor-induced hypotension: implications for the involvement of nitric oxide.

Clinical assessment of the activity of tumor necrosis factor (TNF) against human cancer has been limited by a dose-dependent cardiovascular toxicity, most frequently hypotension. TNF is also thought to mediate the vascular collapse resulting from bacterial endotoxin. The present studies address the...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Kilbourn, R G, Gross, S S, Jubran, A, Adams, J, Griffith, O W, Levi, R, Lodato, R F
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53955/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2333306/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.9.3629
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