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Optogenetic approaches for dissecting neuromodulation and GPCR signaling in neural circuits

Optogenetics has revolutionized neuroscience by providing means to control cell signaling with spatiotemporal control in discrete cell types. In this review, we summarize four major classes of optical tools to manipulate neuromodulatory GPCR signaling: opsins (including engineered chimeric receptors...

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Bibliografiske detaljer
Udgivet i:Curr Opin Pharmacol
Main Authors: Spangler, Skylar M., Bruchas, Michael R.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395328/
https://ncbi.nlm.nih.gov/pubmed/27875804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2016.11.001
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