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PKC-epsilon and TLR4 synergistically regulate resistin-mediated inflammation in human macrophages

BACKGROUND AND AIMS: Resistin has been associated with atherosclerotic inflammation and cardiovascular complications. We and others have previously shown that PKC-epsilon (PKCε) is involved in resistin-induced smooth muscle cell (VSMC) dysfunction at a high pathological concentration. This study aim...

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Опубликовано в: :Atherosclerosis
Главные авторы: Zuniga, Mary C., Raghuraman, Gayatri, Hitchner, Elizabeth, Weyand, Cornelia, Robinson, William, Zhou, Wei
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5395299/
https://ncbi.nlm.nih.gov/pubmed/28286252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2017.02.021
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