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New developments in the treatment of multiple myeloma – clinical utility of daratumumab
Multiple myeloma is a clonal disorder of plasma cells that is currently considered incurable. CD38 is a 46 kDa type II transmembrane glycoprotein that is highly expressed on myeloma cells. Daratumumab is a first in-class human IgG1 monoclonal antibody that targets CD38, and has antimyeloma effects t...
Kaydedildi:
Yayımlandı: | Biologics |
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Asıl Yazarlar: | , , |
Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
Dove Medical Press
2017
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5395289/ https://ncbi.nlm.nih.gov/pubmed/28442888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BTT.S97633 |
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