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New developments in the treatment of multiple myeloma – clinical utility of daratumumab
Multiple myeloma is a clonal disorder of plasma cells that is currently considered incurable. CD38 is a 46 kDa type II transmembrane glycoprotein that is highly expressed on myeloma cells. Daratumumab is a first in-class human IgG1 monoclonal antibody that targets CD38, and has antimyeloma effects t...
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| Published in: | Biologics |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Dove Medical Press
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5395289/ https://ncbi.nlm.nih.gov/pubmed/28442888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BTT.S97633 |
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