ZO-1 interactions with F-actin and occludin direct epithelial polarization and single lumen specification in 3D culture

Epithelia within tubular organs form and expand lumens. Failure of these processes can result in serious developmental anomalies. Although tight junction assembly is crucial to epithelial polarization, the contribution of specific tight junction proteins to lumenogenesis is undefined. Here, we show...

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Udgivet i:J Cell Sci
Main Authors: Odenwald, Matthew A., Choi, Wangsun, Buckley, Aaron, Shashikanth, Nitesh, Joseph, Nora E., Wang, Yitang, Warren, Michael H., Buschmann, Mary M., Pavlyuk, Roman, Hildebrand, Jeffrey, Margolis, Ben, Fanning, Alan S., Turner, Jerrold R.
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394778/
https://ncbi.nlm.nih.gov/pubmed/27802160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.188185
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