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Known mutator alleles do not markedly increase mutation rate in clinical Saccharomyces cerevisiae strains

Natural selection has the potential to act on all phenotypes, including genomic mutation rate. Classic evolutionary theory predicts that in asexual populations, mutator alleles, which cause high mutation rates, can fix due to linkage with beneficial mutations. This phenomenon has been demonstrated e...

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Detalhes bibliográficos
Publicado no:Proc Biol Sci
Main Authors: Skelly, Daniel A., Magwene, Paul M., Meeks, Brianna, Murphy, Helen A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394658/
https://ncbi.nlm.nih.gov/pubmed/28404772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2016.2672
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