Protein 4.1R Exon 16 3′ Splice Site Activation Requires Coordination among TIA1, Pcbp1, and RBM39 during Terminal Erythropoiesis

Exon 16 of protein 4.1R encodes a spectrin/actin-binding peptide critical for erythrocyte membrane stability. Its expression during erythroid differentiation is regulated by alternative pre-mRNA splicing. A UUUUCCCCCC motif situated between the branch point and the 3′ splice site is crucial for incl...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Huang, Shu-Ching, Zhang, Henry S., Yu, Brian, McMahon, Ellen, Nguyen, Dan T., Yu, Faye H., Ou, Alexander C., Ou, Jennie Park, Benz, Edward J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394280/
https://ncbi.nlm.nih.gov/pubmed/28193846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00446-16
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