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Computational identification of mutually exclusive transcriptional drivers dysregulating metastatic microRNAs in prostate cancer

Androgen-ablation therapies, which are the standard treatment for metastatic prostate cancer, invariably lead to acquired resistance. Hence, a systematic identification of additional drivers may provide useful insights into the development of effective therapies. Numerous microRNAs that are critical...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Xue, Mengzhu, Liu, Haiyue, Zhang, Liwen, Chang, Hongyuan, Liu, Yuwei, Du, Shaowei, Yang, Yingqun, Wang, Peng
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394245/
https://ncbi.nlm.nih.gov/pubmed/28397780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14917
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