Negative feedback loop of bone resorption by NFATc1-dependent induction of Cadm1

Trimethylation of histone H3 lysine 4 and lysine 27 (H3K4me3 and H3K27me3) at gene promoter regions critically regulates gene expression. Key developmental genes tend to exhibit changes in histone modification patterns from the H3K4me3/H3K27me3 bivalent pattern to the H3K4me3 monovalent pattern. Usi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nakamura, Shinya, Koyama, Takuma, Izawa, Naohiro, Nomura, Seitaro, Fujita, Takanori, Omata, Yasunori, Minami, Takashi, Matsumoto, Morio, Nakamura, Masaya, Fujita-Jimbo, Eriko, Momoi, Takashi, Miyamoto, Takeshi, Aburatani, Hiroyuki, Tanaka, Sakae
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393607/
https://ncbi.nlm.nih.gov/pubmed/28414795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175632
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