A Patient With a Thyrotropin-Secreting Microadenoma and Resistance to Thyroid Hormone (P453T)

CONTEXT: Resistance to thyroid hormone (RTH) β is due to mutations in the β-isoform of the thyroid hormone receptor (TR). TSH-secreting adenomas (TSHomas) are presumed to represent clonal expansion and have been reported to contain TRβ gene mutations. Mice with a knock-in mutation in the TRβ gene sp...

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Bibliographic Details
Published in:J Clin Endocrinol Metab
Main Authors: Teng, Xiaochun, Jin, Ting, Brent, Gregory A., Wu, Anhua, Teng, Weiping, Shan, Zhongyan
Format: Artigo
Language:Inglês
Published: Endocrine Society 2015
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Special Features
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393528/
https://ncbi.nlm.nih.gov/pubmed/25867808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-3994
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