Differential Response to High Glucose in Skin Fibroblasts of Monozygotic Twins Discordant for Type 1 Diabetes

CONTEXT: Most epigenetic studies in diabetes compare normal cells in “high glucose” (HG) to cells in “normal glucose” (NG) and cells returned from HG to NG. Here we challenge this approach. OBJECTIVE: The objective was to determine whether there were differences in gene expression in skin fibroblast...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Principais autores: Caramori, M. Luiza, Kim, Youngki, Natarajan, Rama, Moore, Jason H., Rich, Stephen S., Mychaleckyj, Josyf C., Kuriyama, Ryoko, Kirkpatrick, David, Mauer, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
Assuntos:
JCEM Online: Advances in Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393515/
https://ncbi.nlm.nih.gov/pubmed/25901990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-4467
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