Genotype-Specific Differences in the Tumor Metabolite Profile of Pheochromocytoma and Paraganglioma Using Untargeted and Targeted Metabolomics

CONTEXT AND OBJECTIVE: Pheochromocytomas and paragangliomas (PGLs) are neuroendocrine tumors of sympathetic or parasympathetic paraganglia. Nearly 40% of PGLs are caused by germline mutations. The present study investigated the effect of genetic alterations on metabolic networks in PGLs. DESIGN: Hom...

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Bibliographic Details
Published in:J Clin Endocrinol Metab
Main Authors: Rao, J. U., Engelke, U. F. H., Sweep, F. C. G. J., Pacak, K., Kusters, B., Goudswaard, A. G., Hermus, A. R. M. M., Mensenkamp, A. R., Eisenhofer, G., Qin, N., Richter, S., Kunst, H. P. M., Timmers, H. J. L. M., Wevers, R. A.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2015
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Hot Topics in Translational Endocrinology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393507/
https://ncbi.nlm.nih.gov/pubmed/25459911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-2138
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