Amino acid residues that affect interaction of tissue-type plasminogen activator with plasminogen activator inhibitor 1.

Fibrinolysis is regulated in part by the interaction between tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor 1 (PAI-1, a serine protease inhibitor of the serpin family). It is known from our earlier work that deletion of a loop of amino acids (residues 296-302) from the...

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Bibliographic Details
Main Authors: Madison, E L, Goldsmith, E J, Gerard, R D, Gething, M J, Sambrook, J F, Bassel-Duby, R S
Format: Artigo
Language:Inglês
Published: 1990
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC53935/
https://ncbi.nlm.nih.gov/pubmed/2110366
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