Epstein–Barr Virus Lytic Reactivation Activates B Cells Polyclonally and Induces Activation-Induced Cytidine Deaminase Expression: A Mechanism Underlying Autoimmunity and Its Contribution to Graves' Disease

Graves' disease is an autoimmune disease that results in and is the most common cause of hyperthyroidism, and the reactivation of persisting Epstein–Barr virus (EBV) in B lymphocytes induces the differentiation of host B cells into plasma cells. We previously reported that some EBV-infected B c...

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Detalles Bibliográficos
Publicado en:Viral Immunol
Main Authors: Nagata, Keiko, Kumata, Keisuke, Nakayama, Yuji, Satoh, Yukio, Sugihara, Hirotsugu, Hara, Sayuri, Matsushita, Michiko, Kuwamoto, Satoshi, Kato, Masako, Murakami, Ichiro, Hayashi, Kazuhiko
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2017
Assuntos:
Original Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393416/
https://ncbi.nlm.nih.gov/pubmed/28333576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vim.2016.0179
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