Epstein–Barr Virus Lytic Reactivation Activates B Cells Polyclonally and Induces Activation-Induced Cytidine Deaminase Expression: A Mechanism Underlying Autoimmunity and Its Contribution to Graves' Disease

Graves' disease is an autoimmune disease that results in and is the most common cause of hyperthyroidism, and the reactivation of persisting Epstein–Barr virus (EBV) in B lymphocytes induces the differentiation of host B cells into plasma cells. We previously reported that some EBV-infected B c...

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Библиографические подробности
Опубликовано в: :Viral Immunol
Главные авторы: Nagata, Keiko, Kumata, Keisuke, Nakayama, Yuji, Satoh, Yukio, Sugihara, Hirotsugu, Hara, Sayuri, Matsushita, Michiko, Kuwamoto, Satoshi, Kato, Masako, Murakami, Ichiro, Hayashi, Kazuhiko
Формат: Artigo
Язык:Inglês
Опубликовано: Mary Ann Liebert, Inc. 2017
Предметы:
Original Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393416/
https://ncbi.nlm.nih.gov/pubmed/28333576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vim.2016.0179
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