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Structure-function studies link class II viral fusogens with the ancestral gamete fusion protein HAP2
The conserved transmembrane protein, HAP2/GCS1, has been linked to fertility in a wide range of taxa and is hypothesized to be an ancient gamete fusogen. Using template-based homology modeling, we now show that the ectodomain of HAP2 orthologs from Tetrahymena thermophila and other species adopt a p...
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| Veröffentlicht in: | Curr Biol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5393271/ https://ncbi.nlm.nih.gov/pubmed/28238660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.01.049 |
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