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Pore translocation of knotted DNA rings

We use an accurate coarse-grained model for DNA and stochastic molecular dynamics simulations to study the pore translocation of 10-kbp–long DNA rings that are knotted. By monitoring various topological and physical observables we find that there is not one, as previously assumed, but rather two qua...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Suma, Antonio, Micheletti, Cristian
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393256/
https://ncbi.nlm.nih.gov/pubmed/28351979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701321114
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