Structural basis of mitochondrial dysfunction in response to cytochrome c phosphorylation at tyrosine 48

Regulation of mitochondrial activity allows cells to adapt to changing conditions and to control oxidative stress, and its dysfunction can lead to hypoxia-dependent pathologies such as ischemia and cancer. Although cytochrome c phosphorylation—in particular, at tyrosine 48—is a key modulator of mito...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Moreno-Beltrán, Blas, Guerra-Castellano, Alejandra, Díaz-Quintana, Antonio, Del Conte, Rebecca, García-Mauriño, Sofía M., Díaz-Moreno, Sofía, González-Arzola, Katiuska, Santos-Ocaña, Carlos, Velázquez-Campoy, Adrián, De la Rosa, Miguel A., Turano, Paola, Díaz-Moreno, Irene
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393209/
https://ncbi.nlm.nih.gov/pubmed/28348229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1618008114
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