Cloning and expression of a mammalian peptide chain release factor with sequence similarity to tryptophanyl-tRNA synthetases.

The termination of protein synthesis is encoded by in-frame nonsense (stop) codons. Most organisms use three nonsense codons: UGA, UAG, and UAA. In contrast to sense codons, which are decoded by specific tRNAs, nonsense codons are decoded by proteins called release factors (RFs). Here we report the...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Lee, C C, Craigen, W J, Muzny, D M, Harlow, E, Caskey, C T
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 1990
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53930/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2185472/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.9.3508
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