Genome-wide DNA methylation measurements in prostate tissues uncovers novel prostate cancer diagnostic biomarkers and transcription factor binding patterns

BACKGROUND: Current diagnostic tools for prostate cancer lack specificity and sensitivity for detecting very early lesions. DNA methylation is a stable genomic modification that is detectable in peripheral patient fluids such as urine and blood plasma that could serve as a non-invasive diagnostic bi...

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Bibliografski detalji
Izdano u:BMC Cancer
Glavni autori: Kirby, Marie K., Ramaker, Ryne C., Roberts, Brian S., Lasseigne, Brittany N., Gunther, David S., Burwell, Todd C., Davis, Nicholas S., Gulzar, Zulfiqar G., Absher, Devin M., Cooper, Sara J., Brooks, James D., Myers, Richard M.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392915/
https://ncbi.nlm.nih.gov/pubmed/28412973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3252-2
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