Genome-wide DNA methylation measurements in prostate tissues uncovers novel prostate cancer diagnostic biomarkers and transcription factor binding patterns

BACKGROUND: Current diagnostic tools for prostate cancer lack specificity and sensitivity for detecting very early lesions. DNA methylation is a stable genomic modification that is detectable in peripheral patient fluids such as urine and blood plasma that could serve as a non-invasive diagnostic bi...

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Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Kirby, Marie K., Ramaker, Ryne C., Roberts, Brian S., Lasseigne, Brittany N., Gunther, David S., Burwell, Todd C., Davis, Nicholas S., Gulzar, Zulfiqar G., Absher, Devin M., Cooper, Sara J., Brooks, James D., Myers, Richard M.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392915/
https://ncbi.nlm.nih.gov/pubmed/28412973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3252-2
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