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X-ray Structure of the Carboplatin-Loaded Apo-Ferritin Nanocage

[Image: see text] The second-generation Pt anticancer agent carboplatin (CBDCA) was encapsulated within the apo horse spleen ferritin (AFt) nanocage, and the X-ray structure of the drug-loaded protein was refined at 1.49 Å resolution. Two Pt binding sites, different from the one observed in the cisp...

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Detaylı Bibliyografya
Yayımlandı:ACS Med Chem Lett
Asıl Yazarlar: Pontillo, Nicola, Ferraro, Giarita, Helliwell, John R., Amoresano, Angela, Merlino, Antonello
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2017
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392753/
https://ncbi.nlm.nih.gov/pubmed/28435532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00025
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