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Calibration and assessment of channel-specific biases in microarray data with extended dynamical range

BACKGROUND: Non-linearities in observed log-ratios of gene expressions, also known as intensity dependent log-ratios, can often be accounted for by global biases in the two channels being compared. Any step in a microarray process may introduce such offsets and in this article we study the biases in...

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Autors principals: Bengtsson, Henrik, Jönsson, Göran, Vallon-Christersson, Johan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC539274/
https://ncbi.nlm.nih.gov/pubmed/15541170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-5-177
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