TET2 and MEG3 promoter methylation is associated with acute myeloid leukemia in a Hainan population

The promoter of MEG3, which encodes the long non-coding RNA (lncRNA) MEG3, is often hypermethylated in acute myeloid leukemia (AML). Additionally, the Tet methylcytosine dioxygenase 2 gene (TET2) is frequently inactivated, which can lead to impaired DNA methylation and promote AML development. We ex...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yao, Hongxia, Duan, Mengling, Lin, Lie, Wu, Congming, Fu, Xiangjun, Wang, Hua, Guo, Li, Chen, Wenting, Huang, Li, Liu, Dan, Rao, Ruo, Wang, Shuwen, Ding, Yipeng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392332/
https://ncbi.nlm.nih.gov/pubmed/28407691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15440
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