EZH2 expression is a prognostic biomarker in patients with colorectal cancer treated with anti-EGFR therapeutics

The polycomb group protein enhancer of zeste homolog 2 (EZH2) is a methyltransferase that suppresses microRNA-31 (miR-31) in various human malignancies including colorectal cancer. We recently suggested that miR-31 regulates the signaling pathway downstream of epidermal growth factor receptor (EGFR)...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yamamoto, Itaru, Nosho, Katsuhiko, Kanno, Shinichi, Igarashi, Hisayoshi, Kurihara, Hiroyoshi, Ishigami, Keisuke, Ishiguro, Kazuya, Mitsuhashi, Kei, Maruyama, Reo, Koide, Hideyuki, Okuda, Hiroyuki, Hasegawa, Tadashi, Sukawa, Yasutaka, Okita, Kenji, Takemasa, Ichiro, Yamamoto, Hiroyuki, Shinomura, Yasuhisa, Nakase, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392288/
https://ncbi.nlm.nih.gov/pubmed/28147317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14863
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