Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition

Runx1 is a well characterized transcription factor essential for hematopoietic differentiation and Runx1 mutations are the cause of leukemias. Runx1 is highly expressed in normal epithelium of most glands and recently has been associated with solid tumors. Notably, the function of Runx1 in the mamma...

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Vydáno v:Oncotarget
Hlavní autoři: Hong, Deli, Messier, Terri L., Tye, Coralee E., Dobson, Jason R., Fritz, Andrew J., Sikora, Kenneth R., Browne, Gillian, Stein, Janet L., Lian, Jane B., Stein, Gary S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392273/
https://ncbi.nlm.nih.gov/pubmed/28407681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15381
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