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Earlier Endpoints Are Required for Hemorrhagic Shock Trials among Severely Injured Patients

BACKGROUND: Choosing the appropriate endpoint for a trauma hemorrhage control trial can determine the likelihood of its success. Recent Phase 3 trials and observational studies have used 24-hour and/or 30-day all-cause mortality as the primary endpoint and some have not used exception from informed...

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Detalhes bibliográficos
Publicado no:Shock
Main Authors: Fox, Erin E., Holcomb, John B., Wade, Charles E., Bulger, Eileen M., Tilley, Barbara C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392160/
https://ncbi.nlm.nih.gov/pubmed/28207628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000788
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