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Stay tuned to PXR: an orphan actor that may not be D-structive only to bone

Pregnane X receptor (PXR) plays an important role in detoxifying xenobiotics and drugs. In this issue of the JCI, Pascussi et al. provide convincing evidence that PXR can also induce vitamin D deficiency and bone disease because of its ability to cross-talk with the vitamin D–responsive gene that ca...

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Detalhes bibliográficos
Autor principal: Holick, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC539210/
https://ncbi.nlm.nih.gov/pubmed/15630441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200523995
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