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Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair

Macrophages perform both injury-inducing and repair-promoting tasks in different models of inflammation, leading to a model of macrophage function in which distinct patterns of activation have been proposed. We investigated macrophage function mechanistically in a reversible model of liver injury in...

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Bibliografiske detaljer
Main Authors: Duffield, Jeremy S., Forbes, Stuart J., Constandinou, Christothea M., Clay, Spike, Partolina, Marina, Vuthoori, Srilatha, Wu, Shengji, Lang, Richard, Iredale, John P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC539199/
https://ncbi.nlm.nih.gov/pubmed/15630444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200522675
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