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Comparison of independent screens on differentially vulnerable motor neurons reveals alpha-synuclein as a common modifier in motor neuron diseases

The term “motor neuron disease” encompasses a spectrum of disorders in which motor neurons are the primary pathological target. However, in both patients and animal models of these diseases, not all motor neurons are equally vulnerable, in that while some motor neurons are lost very early in disease...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Kline, Rachel A., Kaifer, Kevin A., Osman, Erkan Y., Carella, Francesco, Tiberi, Ariana, Ross, Jolill, Pennetta, Giuseppa, Lorson, Christian L., Murray, Lyndsay M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391970/
https://ncbi.nlm.nih.gov/pubmed/28362802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006680
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