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Inherited variants in genes somatically mutated in thyroid cancer

BACKGROUND: Tumour suppressor genes when mutated in the germline cause various cancers, but they can also be somatically mutated in sporadic tumours. We hypothesized that there may also be cancer-related germline variants in the genes commonly mutated in sporadic well-differentiated thyroid cancer (...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Campo, Chiara, Köhler, Aleksandra, Figlioli, Gisella, Elisei, Rossella, Romei, Cristina, Cipollini, Monica, Bambi, Franco, Hemminki, Kari, Gemignani, Federica, Landi, Stefano, Försti, Asta
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391920/
https://ncbi.nlm.nih.gov/pubmed/28410400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174995
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