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miR-483 Targeting of CTGF Suppresses Endothelial-to-Mesenchymal Transition: Therapeutic Implications in Kawasaki Disease

RATIONALE: Endothelial-to-mesenchymal transition (EndoMT) is implicated in myofibroblast-like cell-mediated damage to the coronary arterial wall in acute Kawasaki disease (KD) patients, as evidenced by positive staining for connective tissue growth factor (CTGF) and EndoMT markers in KD autopsy tiss...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: He, Ming, Chen, Zhen, Martin, Marcy, Zhang, Jin, Sangwung, Panjamaporn, Woo, Brian, Tremoulet, Adriana H., Shimizu, Chisato, Jain, Mukesh K., Burns, Jane C., Shyy, John Y-J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391835/
https://ncbi.nlm.nih.gov/pubmed/27923814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.310233
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