Alteration of Neuronal Excitability and Short-Term Synaptic Plasticity in the Prefrontal Cortex of a Mouse Model of Mental Illness

Using a genetic mouse model that faithfully recapitulates a DISC1 genetic alteration strongly associated with schizophrenia and other psychiatric disorders, we examined the impact of this mutation within the prefrontal cortex. Although cortical layering, cytoarchitecture, and proteome were found to...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Crabtree, Gregg W., Sun, Ziyi, Kvajo, Mirna, Broek, Jantine A.C., Fénelon, Karine, McKellar, Heather, Xiao, Lan, Xu, Bin, Bahn, Sabine, O'Donnell, James M., Gogos, Joseph A.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2017
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391686/
https://ncbi.nlm.nih.gov/pubmed/28283561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4345-15.2017
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