Toll-like receptor 4 in glial inflammatory responses to air pollution in vitro and in vivo

BACKGROUND: Exposure to traffic-related air pollution (TRAP) is associated with accelerated cognitive aging and higher dementia risk in human populations. Rodent brains respond to TRAP with activation of astrocytes and microglia, increased inflammatory cytokines, and neurite atrophy. A role for Toll...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Woodward, Nicholas C., Levine, Morgan C., Haghani, Amin, Shirmohammadi, Farimah, Saffari, Arian, Sioutas, Constantinos, Morgan, Todd E., Finch, Caleb E.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391610/
https://ncbi.nlm.nih.gov/pubmed/28410596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0858-x
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