Comparison of different cell type correction methods for genome-scale epigenetics studies

BACKGROUND: Whole blood is frequently utilized in genome-wide association studies of DNA methylation patterns in relation to environmental exposures or clinical outcomes. These associations can be confounded by cellular heterogeneity. Algorithms have been developed to measure or adjust for this hete...

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Udgivet i:BMC Bioinformatics
Main Authors: Kaushal, Akhilesh, Zhang, Hongmei, Karmaus, Wilfried J. J., Ray, Meredith, Torres, Mylin A., Smith, Alicia K., Wang, Shu-Li
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391562/
https://ncbi.nlm.nih.gov/pubmed/28410574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1611-2
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