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Comparison of different cell type correction methods for genome-scale epigenetics studies

BACKGROUND: Whole blood is frequently utilized in genome-wide association studies of DNA methylation patterns in relation to environmental exposures or clinical outcomes. These associations can be confounded by cellular heterogeneity. Algorithms have been developed to measure or adjust for this hete...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Kaushal, Akhilesh, Zhang, Hongmei, Karmaus, Wilfried J. J., Ray, Meredith, Torres, Mylin A., Smith, Alicia K., Wang, Shu-Li
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391562/
https://ncbi.nlm.nih.gov/pubmed/28410574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1611-2
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