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A mutant neomycin phosphotransferase II gene reduces the resistance of transformants to antibiotic selection pressure.

The neo (neomycin-resistance) gene of transposon Tn5 encodes the enzyme neomycin phosphotransferase II (EC 2.7.1.95), which confers resistance to various aminoglycoside antibiotics, including kanamycin and G418. The gene is widely used as a selectable marker in the transformation of organisms as div...

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Autori principali: Yenofsky, R L, Fine, M, Pellow, J W
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1990
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC53915/
https://ncbi.nlm.nih.gov/pubmed/2159150
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