Genomic deletion of GIT2 induces a premature age-related thymic dysfunction and systemic immune system disruption

Recent research has proposed that GIT2 (G protein-coupled receptor kinase interacting protein 2) acts as an integrator of the aging process through regulation of ‘neurometabolic’ integrity. One of the commonly accepted hallmarks of the aging process is thymic involution. At a relatively young age, 1...

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Foilsithe in:Aging (Albany NY)
Main Authors: Siddiqui, Sana, Lustig, Ana, Carter, Arnell, Sankar, Mathavi, Daimon, Caitlin M., Premont, Richard T., Etienne, Harmonie, van Gastel, Jaana, Azmi, Abdelkrim, Janssens, Jonathan, Becker, Kevin G., Zhang, Yongqing, Wood, William, Lehrmann, Elin, Martin, James G., Martin, Bronwen, Taub, Dennis D., Maudsley, Stuart
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2017
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391227/
https://ncbi.nlm.nih.gov/pubmed/28260693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101185
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