Angiopoietin-2 in white adipose tissue improves metabolic homeostasis through enhanced angiogenesis

Despite many angiogenic factors playing crucial roles in metabolic homeostasis, effects of angiopoietin-2 (ANG-2) in adipose tissue (AT) remain unclear. Utilizing a doxycycline-inducible AT-specific ANG-2 overexpression mouse model, we assessed the effects of ANG-2 in AT expansion upon a high-fat di...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: An, Yu A, Sun, Kai, Joffin, Nolwenn, Zhang, Fang, Deng, Yingfeng, Donzé, Olivier, Kusminski, Christine M, Scherer, Philipp E
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5391203/
https://ncbi.nlm.nih.gov/pubmed/28355132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.24071
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